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4-hydroxybenzoate biosynthesis I (eukaryotes)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-tyrosine + 2-oxoglutarate <=> 4-hydroxyphenylpyruvate + L-glutamate 2.6.1.1 aspartate transaminase
2.6.1.2 alanine transaminase
2.6.1.24 diiodotyrosine transaminase
2.6.1.27 tryptophan transaminase
2.6.1.39 2-aminoadipate transaminase
2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.49 dihydroxyphenylalanine transaminase
2.6.1.5 tyrosine transaminase
2.6.1.57 aromatic-amino-acid transaminase
2.6.1.7 kynurenine---oxoglutarate transaminase
2.6.1.79 glutamate---prephenate aminotransferase
2.6.1.9 histidinol-phosphate transaminase












(R)-3-(4-hydroxyphenyl)lactate + NAD+ <=> 4-hydroxyphenylpyruvate + NADH + H+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.222 (R)-4-hydroxyphenyllactate dehydrogenase
1.1.1.237 hydroxyphenylpyruvate reductase
1.1.1.345 D-2-hydroxyacid dehydrogenase (NAD+)
1.1.1.37 malate dehydrogenase
1.1.1.96 diiodophenylpyruvate reductase






4-coumaroyl-CoA + (R)-3-(4-hydroxyphenyl)lactate <=> p-coumaric_acid + (R)-3-(4-hydroxyphenyl)lactoyl-CoA 2.8.3.17 3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase

p-coumaric_acid + H2O <=> 4-hydroxybenzaldehyde + acetate 3.7.1

4-hydroxybenzaldehyde + NAD+ + H2O <=> 4-hydroxybenzoate + NADH + H+ 1.2.1.28 benzaldehyde dehydrogenase (NAD+)
1.2.1.29 aryl-aldehyde dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.64 4-hydroxybenzaldehyde dehydrogenase (NAD+)
1.2.1.65 salicylaldehyde dehydrogenase
1.2.1.67 vanillin dehydrogenase
1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)







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